Disease of Calcium channel
1-Voltage-gated
a-CACNA1A “Cav2.1, P/Q voltage-dependent calcium channel“: Familial hemiplegic migraine, Episodic ataxia, Spinocerebellar ataxia type-6
b-CACNA1C “Calcium channel, voltage-dependent, L type, alpha 1C subunit ( Cav1.2)“: Timothy syndrome, Brugada syndrome, Long QT syndrome 8
c-CACNA1F “Cav1.4 calcium channel, voltage-dependent, L type, alpha 1F subunit“: Ocular albinism 2, CSNB2A “Congenital stationary night blindness”
d-CACNA1S “Cav1.1 calcium channel, voltage-dependent, L type, alpha 1S subunit“: Hypokalemic periodic paralysis, Thyrotoxic periodic paralysis
e-CACNB2 “Voltage-dependent L-type calcium channel subunit beta-2“: Brugada syndrome
2-Ligand gated
a-RYR1 “Ryanodine receptor 1 (RYR-1), skeletal muscle calcium release channel / skeletal muscle-type ryanodine receptor“: Malignant hyperthermia, Central core disease
b-RYR2 “Ryanodine receptor 2“: CPVT1” Catecholaminergic polymorphic ventricular tachycardia”, ARVD2 “Arrhythmogenic cardiomyopathy”