Ileal sodium/bile acid cotransporter “IBAT” inhibitors

Ileal sodium/bile acid cotransporter IBAT inhibitors;

Several medications to inhibit IBAT are under development.

1-They include elobixibat, under development for the treatment of constipation and irritable bowel syndrome, and

2-Volixibat, under development for the treatment of nonalcoholic steatohepatitis.

3-İn Alagille syndrome; Maralixibat chloride is an ileal bile acid transporter (IBAT) inhibitor.