DNA precursors/ antimetabolites (S phase)
I-Folic acid
Dihydrofolate reductase inhibitör (Aminopterin, Methotrexate, Pemetrexed, Pralatrexate)
Thymidylate synthase inhibitor (Pemetrexed, Raltitrexed)
II-Purine
Adenosine deaminase inhibitor (Pentostatin)
Halogenated/ribonucleotide reductase inhibitors (Cladribine, Clofarabine, Fludarabine)
Nelarabine
Rabacfosadine
Thiopurine (Mercaptopurine,Tioguanine)
III-Pyrimidine
Thymidylate synthase inhibitor (Capecitabine, Carmofur, Doxifluridine, Floxuridine, Fluorouracil, Tegafur (+gimeracil/oteracil))
DNA polymerase inhibitor (Cytarabine, daunorubicin)
Ribonucleotide reductase inhibitor (Gemcitabine)
Hypomethylating agent (Azacitidine, Decitabine)
IV-Deoxyribonucleotide
Ribonucleotide reductase inhibitor (Hydroxycarbamide )