| Type I/allergy/atopy (IgE) | Foreign Allergic asthma Allergic urticaria Allergic rhinitis (Hay fever) Anaphylaxis Atopic dermatitis Food allergy common allergies include: “Egg, Milk, Peanut, Seafood, Soy, Tree nut, Wheat “ Penicillin allergy II-Autoimmune Autoimmune urticaria Eosinophilic esophagitis |
| List of a few mediators released by mast cells in type 1 hypersensitivity and their actions | |
| Vasodilation and increased permeability | Histamine PAF Leukotriene C4, D4, and E4 Prostaglandin D2 Neutral proteases |
| Smooth muscle spasm | Histamine PAF Leukotriene C4, D4, and E4 Prostaglandin |
| Leukocyte extravasation | Cytokines (e.g. chemokines and TNF) Leukotriene B4 Chemotactic factors for neutrophils and eosinophils |
| Unless otherwise specified, the reference for this table is: | |