| Translocation | Associated diseases | Fused genes/proteins | |
| First | Second | ||
| t(8;14)(q24;q32) | Burkitt’s lymphoma | c-myc on chromosome 8, gives the fusion protein lymphocyte-proliferative ability | IGH@ (immunoglobulin heavy locus) on chromosome 14, induces massive transcription of fusion protein |
| t(11;14)(q13;q32) | Mantle cell lymphoma | cyclin D1 on chromosome 11, gives fusion protein cell-proliferative ability | IGH@ (immunoglobulin heavy locus) on chromosome 14, induces massive transcription of fusion protein |
| t(14;18)(q32;q21) | Follicular lymphoma (~90% of cases) | IGH@ (immunoglobulin heavy locus) on chromosome 14, induces massive transcription of fusion protein | Bcl-2 on chromosome 18, gives fusion protein anti-apoptotic abilities |
| t(10;(various))(q11;(various)) | Papillary thyroid cancer | RET proto-oncogene on chromosome 10 | PTC (Papillary Thyroid Cancer) – Placeholder for any of several other genes/proteins |
| t(2;3)(q13;p25) | Follicular thyroid cancer | PAX8 – paired box gene 8 on chromosome 2 | PPARγ1 (peroxisome proliferator-activated receptor γ 1) on chromosome 3 |
| t(8;21)(q22;q22) | Acute myeloblastic leukemia with maturation | ETO on chromosome 8 | AML1 on chromosome 21 found in ~7% of new cases of AML, carries a favorable prognosis and predicts good response to cytosine arabinoside therapy |
| t(9;22)(q34;q11) Philadelphia chromosome | Chronic myelogenous leukemia (CML), acute lymphoblastic leukemia (ALL) | Abl1 gene on chromosome 9 | BCR (“breakpoint cluster region” on chromosome 22 |
| t(15;17)(q22;q21) | Acute promyelocytic leukemia | PML protein on chromosome 15 | RAR-α on chromosome 17 persistent laboratory detection of the PML-RARA transcript is strong predictor of relapse[ |
| t(12;15)(p13;q25) | Acute myeloid leukemia, congenital fibrosarcoma, secretory breast carcinoma, mammary analogue secretory carcinoma of salivary glands, cellular variant of mesoblastic nephroma | TEL on chromosome 12 | TrkC receptor on chromosome 15 |
| t(9;12)(p24;p13) | CML, ALL | JAK on chromosome 9 | TEL on chromosome 12 |
| t(12;16)(q13;p11) | Myxoid liposarcoma | DDIT3 (formerly CHOP) on chromosome 12 | FUS gene on chromosome 16 |
| t(12;21)(p12;q22) | ALL | TEL on chromosome 12 | AML1 on chromosome 21 |
| t(11;18)(q21;q21) | MALT lymphoma | BIRC3 (API-2) | MLT |
| t(1;11)(q42.1;q14.3) | Schizophrenia | ||
| t(2;5)(p23;q35) | Anaplastic large cell lymphoma | ALK | NPM1 |
| t(11;22)(q24;q11.2-12) | Ewing’s sarcoma | FLI1 | EWS |
| t(17;22) | DFSP | Collagen I on chromosome 17 | Platelet derived growth factor B on chromosome 22 |
| t(1;12)(q21;p13) | Acute myelogenous leukemia | ||
| t(X;18)(p11.2;q11.2) | Synovial sarcoma | ||
| t(1;19)(q10;p10) | Oligodendroglioma and oligoastrocytoma | ||
| t(17;19)(q22;p13) | ALL | ||
| t(7,16) (q32-34;p11) or t(11,16) (p11;p11) | Low-grade fibromyxoid sarcoma | FUS | CREB3L2 or CREB3L1 |