1-Type 1 (SAID cluster) “Severe Auto-Immune Diabetes”, TYPE 1A-Autoimmun DM
2-Type 1 diabetes (LADA cluster) “Slowly evolving immune-mediated diabetes, latent autoimmune diabetes in adults “, TYPE 1B-Nonautoimmun DM
3-Type 2 (SIDD, SIRD, MOD and MARD clusters)
a-SIDD (Severe Insulin Deficient Diabetes).
b-SIRD (Severe Insulin Resistant Diabetes).
c-MOD (Mild Obesity-related Diabetes).
d-MARD (Mild Age-Related Diabetes).
4-Type 4 (Gestational diabetes) Diabetes and pregnancy
5-Prediabetes
a-Impaired fasting glucose “Bozulmuş açlık glikozu”
b-Impaired glucose tolerance “Bozulmuş glikoz toleransı”
6-Insulin resistance
7-Ketosis-prone diabetes (KPD) “Ketozise yatkın diyabet “
8-Type 3a (MODY) “Maturity-onset diabetes of the young” “Gençlerin Erişkin Başlangıçlı Diyabeti”
a-MODY Type I “hepatocyte nuclear factor 4α”
b-MODY Type II “glucokinase”
c-MODY Type III “hepatocyte nuclear factor 1α”
d-MODY Type IV “insulin promoter factor-1 “
e-MODY Type V “hepatocyte nuclear factor 1β”
f-MODY Type VI “neurogenic differentiation 1”
9-Neonatal
a-Transient
b-Permanent
10-Type 3c (pancreatogenic)
11-Type 3 “Alzheimer hastalığı ile tip 1 ve tip 2 diyabetin belirli özellikleri arasında önerilen patolojik bir bağlantıdır”
12-MIDD “Diabetes and deafness (DAD), maternally inherited diabetes and deafness (MIDD), mitochondrial diabetes”
a-MT-TL1 “Mitochondrially encoded tRNA leucine 1 (UUA/G)” geni ile ilişkili
b-MT-TE “Mitochondrially encoded tRNA glutamic acid” geni ile ilişkili
c-MT-TK ” Mitochondrially encoded tRNA lysine” geni ile ilişkili
MODY Subclassification
HNF4A-MODY (MODY 1); hepatocyte nuclear factor 4α
GCK-MODY (MODY 2); glucokinase
HNF1A-MODY (MODY 3); hepatocyte nuclear factor 1α
PDX1-MODY (MODY 4); insulin promoter factor-1
HNF1B-MODY (MODY 5); hepatocyte nuclear factor 1β
NEUROD1-MODY (MODY 6); neurogenic differentiation 1
KLF11-MODY (MODY 7); Kruppel-like factor 11
CEL-MODY MODY 8; “Bile salt dependent lipase “
PAX4-MODY MODY 9; PAX4 “Paired box gene 4”
INS-MODY MODY 10; INS “Insulin”
BLK-MODY MODY 11; BLK “Tyrosine-protein kinase BLK, B lymphocyte kinase“
AAPL1-MODY MODY 14; APPL1 “Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1”