1-Tip I (asidik) ve Tip II (bazik) intrasitoplazmik keratinlere örnek, Epithelial keratin ile Trichocytic keratin
Tip II A ilişkili patolojiler; epidermolytic hyperkeratosis (EHK) ve palmoplantar keratoderma (PPK),
Tip II B ile ilişkili patolojiler; psoriasis, epidermolysis bullosa, pachyonychia congenita
2-Tip III
Desmin, Desmin-related myofibrillar myopathy (DRM or desminopathy), urothelial carcinoma, restrictive, dilated, idiopathic, arrhythmogenic ve non-compaction cardimyopathy.
Glial fibrillary acidic protein; Autoimmune GFAP astrocytopathy, Alexander hastalığı, anaplastik astrositom, wernicke ensefalopatisi
Peripherin; “amyotrophic lateral sclerosis, insulin-dependent diabetes mellitus (diabetes mellitus type 1), Hirschsprung disease“
Vimentin; “sarcoma tumor, cystic variant papillary thyroid carcinoma, Anti-citrullinated protein antibody-rheumatoid arthritis“
Syncoilin, hem Tip III hem de tip IV IF içeren mikst bir IF dir.
3-Tip IV
Alpha-internexin; bu intermediate filament ile ilişkili patolojiler, “Alzheimer’s disease, amyotrophic lateral sclerosis, dementia with Lewy bodies, Parkinson’s disease, neuropathies, tropical spastic paraparesis and HTLV-1 associated myelopathy“
Neurofilaments
Synemin; “Human papillomavirus-positive neoplastic keratinocytes ve uterine cervical preneoplastic lesions“
Syncoilin; “Duchenne muscular dystrophy, Becker muscular dystrophy, Central core disease, Congenital muscular dystrophies ve Neurogenic disorder“
4-Tip V
Laminler; Lamin ilişkili patolojiler yani lopatiler; “Hutchinson-Gilford progeria syndrome” ve “Lamin A/C heart-Dilate KMP” disease
5-Tip VI
Filensin; “beaded filament structural protein 1-BFSP1”
Phakinin; “beaded filament structural protein 2“, BFSP2 ilişkili patoloji “Dowling-Meara epidermolysis bullosa simplex” dir.
Nestin;
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Intermediate filaments
1-Type ½ (Keratin, Cytokeratin)
a-Epithelial keratins (soft alpha-keratins)
type I/
chromosome 17
chromosome 12
none 21
type II/
chromosome 12
b-Hair keratins (hard alpha-keratins)
type I/chromosome 17
type II/chromosome 12
c-Ungrouped alpha
chromosome 17
chromosome 12
d-Not alpha
Beta-keratin
2-Type 3
Desmin
GFAP
Peripherin
Vimentin
3-Type 4
Internexin
Nestin
Neurofilament NEFL, NEFM, NEFH
Synemin
Syncoilin
4-Type 5
Nuclear lamins:
A/C
B1
B2